Tinnitus and hyperacusis: central noise, gain and variance
نویسندگان
چکیده
منابع مشابه
Central Gain Control in Tinnitus and Hyperacusis
Sensorineural hearing loss induced by noise or ototoxic drug exposure reduces the neural activity transmitted from the cochlea to the central auditory system. Despite a reduced cochlear output, neural activity from more central auditory structures is paradoxically enhanced at suprathreshold intensities. This compensatory increase in the central auditory activity in response to the loss of senso...
متن کاملAn active loudness model suggesting tinnitus as increased central noise and hyperacusis as increased nonlinear gain.
The present study uses a systems engineering approach to delineate the relationship between tinnitus and hyperacusis as a result of either hearing loss in the ear or an imbalanced state in the brain. Specifically examined is the input-output function, or loudness growth as a function of intensity in both normal and pathological conditions. Tinnitus reduces the output dynamic range by raising th...
متن کاملPathology of Tinnitus and Hyperacusis-Clinical Implications
Not long ago, tinnitus and hyperacusis were considered intractable symptoms and the lack of interest and shortage of research in diseases with these symptoms would have made publishing a special issue on tinnitus and hyperacusis nearly impossible. During the past two decades, there has been an explosion of research on tinnitus and incremental growth on hyperacusis, a condition associated with h...
متن کاملPhenotypic Characteristics of Hyperacusis in Tinnitus
BACKGROUND Many people with tinnitus also suffer from hyperacusis. Both clinical and basic scientific data indicate an overlap in pathophysiologic mechanisms. In order to further elucidate the interplay between tinnitus and hyperacusis we compared clinical and demographic characteristics of tinnitus patients with and without hyperacusis by analyzing a large sample from an international tinnitus...
متن کاملTinnitus and hyperacusis: Contributions of paraflocculus, reticular formation and stress
Tinnitus and hyperacusis are common and potentially serious hearing disorders associated with noise-, age- or drug-induced hearing loss. Accumulating evidence suggests that tinnitus and hyperacusis are linked to excessive neural activity in a distributed brain network that not only includes the central auditory pathway, but also brain regions involved in arousal, emotion, stress and motor contr...
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ژورنال
عنوان ژورنال: Current Opinion in Physiology
سال: 2020
ISSN: 2468-8673
DOI: 10.1016/j.cophys.2020.10.009